Complex ophthalmoplaegia denoting Wernicke encephalopathy in a non-alcoholic individual.

The nucleus basalis (Ch4) in the alcoholic Wernicke-Korsakoff syndrome: reduced cell number in both amnesic and non-amnesic patients.

BACKGROUND The cholinergic nucleus basalis (Ch4) is an exclusive site of neurofibrillary degeneration in alcoholic patients with Wernicke's encephalopathy. AIM To test the hypothesis that the loss of Ch4 neurons contributes to the memory disorder, Korsakoff's psychosis, commonly seen in Wernicke's encephalopathy. METHODS Magnocellular basal forebrain neurons were quantified in alcoholic pat...

The nucleus basalis (Ch4) in the alcoholic Wernicke-KorsakoV syndrome: reduced cell number in both amnesic and non-amnesic patients

Background—The cholinergic nucleus basalis (Ch4) is an exclusive site of neurofibrillary degeneration in alcoholic patients with Wernicke’s encephalopathy. Aim—To test the hypothesis that the loss of Ch4 neurons contributes to thememory disorder, KorsakoV’s psychosis, commonly seen in Wernicke’s encephalopathy. Methods—Magnocellular basal forebrain neurons were quantified in alcoholic patients ...

Wernicke's encephalopathy in a non-alcoholic Patient: Difficulties of early diagnosis and treatment

A case report: Non-alcoholic Wernicke encephalopathy associated with polyneuropathy

We report a rare case of non-alcoholic Wernicke encephalopathy (WE) with polyneuropathy. A 24-year-old woman who had recently served a 4-month prison sentence and underwent a short period of dieting manifested slow response, weakness, language disorder and amnesia. Brain magnetic resonance imaging (MRI) revealed typical lesions of WE. Examination of nerve conduction velocity revealed sensory-mo...

Brain stem auditory evoked responses in chronic alcoholics.

Brain stem auditory evoked responses (BAERs) were performed on 25 alcoholic patients with Wernicke-Korsakoff syndrome, 56 alcoholic patients without Wernicke-Korsakoff syndrome, 24 of whom had cerebellar ataxia, and 37 control subjects. Abnormal BAERs were found in 48% of patients with Wernicke-Korsakoff syndrome, in 25% of alcoholic patients without Wernicke-Korsakoff syndrome but with cerebel...